Targeting the DNA Damage Response for Anti-Cancer Therapy

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Pollard, John (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Curtin, Nicola (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Humana, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Cancer Drug Discovery and Development,
• Θέματα: Cancer research.; Gene therapy.; Cancer Research.; Gene Therapy.

Over the past decade a complex role for DNA damage response (DDR) in tumorigenesis has emerged. A proficient DDR has been shown to be a primary cause for cellular resistance to the very many DNA damaging drugs, and IR, that are widely used as standard-of-care across multiple cancer types. It has als...