Animal Models of T Cell-Mediated Skin Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Zollner, T. (Editor), Renz, H. (Editor), Asadullah, K. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Ernst Schering Research Foundation Workshop, 50
• Subjects: Chemistry.; Medicinal chemistry.; Dermatology.; Internal medicine.; Respiratory organs > Diseases.; Cell biology.; Medicinal Chemistry.; Biomedicine general.; Cell Biology.; Pneumology/Respiratory System.; Internal Medicine.

Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. T...