CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

• Corporate Author: SpringerLink (Online service)
• Other Authors: Compans, R.W (Editor), Cooper, M.D (Editor), Honjo, T. (Editor), Koprowski, H. (Editor), Melchers, F. (Editor), Oldstone, M.B.A (Editor), Olsnes, S. (Editor), Potter, M. (Editor), Vogt, P.K (Editor), Wagner, H. (Editor), Kyewski, Bruno (Editor), Suri-Payer, Elisabeth (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
• Series: Current Topics in Microbiology and Immunology, 293
• Subjects: Medicine.; Immunology.; Biomedicine.

The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-react...