CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential

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The vertebrate immune system defends the organism against invading pathogens while at the same time being self-tolerant to the body’s own constituents thus preserving its integrity. Multiple mechanisms work in concert to ensure self-tolerance. Apart from purging the T cell repertoire from auto-react...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Compans, R.W (Επιμελητής έκδοσης), Cooper, M.D (Επιμελητής έκδοσης), Honjo, T. (Επιμελητής έκδοσης), Koprowski, H. (Επιμελητής έκδοσης), Melchers, F. (Επιμελητής έκδοσης), Oldstone, M.B.A (Επιμελητής έκδοσης), Olsnes, S. (Επιμελητής έκδοσης), Potter, M. (Επιμελητής έκδοσης), Vogt, P.K (Επιμελητής έκδοσης), Wagner, H. (Επιμελητής έκδοσης), Kyewski, Bruno (Επιμελητής έκδοσης), Suri-Payer, Elisabeth (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2005.
Σειρά:Current Topics in Microbiology and Immunology, 293
Θέματα:
Medicine.
Immunology.
Biomedicine.
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Origin and Generation
  • Selection of CD4+CD25+ Regulatory T Cells by Self-Peptides
  • The Role of TCR Specificity in Naturally Arising CD25+ CD4+ Regulatory T Cell Biology
  • Thymic Commitment of Regulatory T Cells Is a Pathway of TCR-Dependent Selection That Isolates Repertoires Undergoing Positive or Negative Selection
  • Selection and Behavior of CD4+ CD25+ T Cells In Vivo: Lessons from T Cell Receptor Transgenic Models
  • Migration Rules: Functional Properties of Naive and Effector/Memory-Like Regulatory T Cell Subsets
  • Peripheral Generation and Function of CD4+CD25+ Regulatory T Cells
  • Dendritic Cells: Key Cells for the Induction of Regulatory T Cells?
  • Involvement of Disease Models
  • Autoimmune Gastritis Is a Well-Defined Autoimmune Disease Model for the Study of CD4+CD25+ T Cell-Mediated Suppression
  • Regulatory T Cells in Experimental Colitis
  • Autoimmune Ovarian Disease in Day 3-Thymectomized Mice: The Neonatal Time Window, Antigen Specificity of Disease Suppression, and Genetic Control
  • Regulatory T Cells in Transplantation Tolerance
  • CD4+CD25+ Regulatory T Cells in Hematopoietic Stem Cell Transplantation
  • Naturally Arising CD25+CD4+ Regulatory T Cells in Tumor Immunity
  • Phenotypic and Functional Differences Between Human CD4+CD25+ and Type 1 Regulatory T Cells.

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