Acute Promyelocytic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Pandolfi, Pier Paolo (Editor), Vogt, Peter K. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.
• Series: Current Topics in Microbiology and Immunology, 313
• Subjects: Medicine.; Cancer research.; Biomedicine.; Cancer Research.

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Table of Contents:

• APL as a Paradigm in Biomedical Research: A Journey Toward the Cure
• Mouse Models of Acute Promyelocytic Leukemia
• The PLZF Gene of t(11;17)-Associated APL
• SUMO, the Three Rs and Cancer
• Emerging Role for MicroRNAs in Acute Promyelocytic Leukemia
• The Theory of APL Revisited
• Treatment of Acute Promyelocytic Leukemia by Retinoids
• Arsenic Trioxide and Acute Promyelocytic Leukemia: Clinical and Biological
• Front Line Clinical Trials and Minimal Residual Disease Monitoring in Acute Promyelocytic Leukemia
• Histone Deacetylase Inhibitors in APL and Beyond
• Monoclonal Antibody Therapy of APL
• Targeting APL Fusion Proteins by Peptide Interference
• The Design of Selective and Non-selective Combination Therapy for Acute Promyelocytic Leukemia.