Tubulin-Binding Agents Synthetic, Structural and Mechanistic Insights /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Carlomagno, Teresa (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2009.
• Series: Topics in Current Chemistry, 286
• Subjects: Chemistry.; Cancer research.; Analytical chemistry.; Organic chemistry.; Medicinal chemistry.; Biochemistry.; Medicinal Chemistry.; Biochemistry, general.; Cancer Research.; Organic Chemistry.; Analytical Chemistry.

reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year pe...