Synaptic Plasticity and the Mechanism of Alzheimer's Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Selkoe, Dennis J. (Επιμελητής έκδοσης), Triller, Antoine (Επιμελητής έκδοσης), Christen, Yves (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg, 2008.
• Σειρά: Research and Perspectives in Alzheimer's Disease,
• Θέματα: Medicine.; Human physiology.; Neurosciences.; Biomedicine.; Human Physiology.

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Πίνακας περιεχομένων:

• Permanence of the Synapse and Molecular Instability
• Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity
• Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo
• Synapse Loss, Synaptic Plasticity and the Postsynaptic Density
• Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity
• Quantitative Neuropathology in Alzheimer’s Mouse Models
• Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States
• Soluble Oligomers of the Amyloid ?-Protein: Impair Synaptic Plasticity and Behavior
• Why Alzheimer’s is a Disease of Memory: Synaptic Targeting by Pathogenic A? Oligomers (ADDLs)
• Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-? Levels
• A?-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP)
• Long-Term Potentiation and A?: Targeting A? Species, Cellular Mechanisms and Putative Receptors
• Genes, Synapses and Autism Spectrum Disorders.