Multiple Myeloma

• Corporate Author: SpringerLink (Online service)
• Other Authors: Moehler, Thomas (Editor), Goldschmidt, Hartmut (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011.
• Series: Recent Results in Cancer Research, 183
• Subjects: Medicine.; Cancer research.; Hematology.; Oncology.; Medicine & Public Health.; Cancer Research.

Multiple myeloma is currently still an incurable disease, but during the past decade knowledge of its molecular pathogenesis has increased rapidly. This has led to remarkable progress in both diagnosis and therapy. In particular, the approval of novel and first-in-class drugs such as thalidomide, bo...

Table of Contents:

• History and epidemiology
• Pathophysiology: Molecular biology of plasma cell disorders. Alterations in microenvironment
• Clinical Features: Imaging. Integrated innovative approach for diagnosis and staging
• Therapy: High-dose chemotherapy and ABSCT
• Allogeneic transplantation. Novel Drugs
• Immunotherapeutic approaches
• First-line treatment and maintenance
• Relapse
• Radiotherapy
• Kyphoplasty
• Supportive Therapy
• Appendix: Staging and prognosis systems.