Coarse-Grained Modelling of DNA and DNA Self-Assembly

• Κύριος συγγραφέας: Ouldridge, Thomas E. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2012.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Physics.; Polymers.; Amorphous substances.; Complex fluids.; Biophysics.; Biological physics.; Statistical physics.; Dynamical systems.; Nanotechnology.; Biophysics and Biological Physics.; Polymer Sciences.; Statistical Physics, Dynamical Systems and Complexity.; Soft and Granular Matter, Complex Fluids and Microfluidics.

This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of s...