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02826nam a22005775i 4500 |
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978-3-642-30517-7 |
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20151204154812.0 |
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120707s2012 gw | s |||| 0|eng d |
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|a 9783642305177
|9 978-3-642-30517-7
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|a 10.1007/978-3-642-30517-7
|2 doi
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|a 571.4
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|a Ouldridge, Thomas E.
|e author.
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|a Coarse-Grained Modelling of DNA and DNA Self-Assembly
|h [electronic resource] /
|c by Thomas E. Ouldridge.
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|a Berlin, Heidelberg :
|b Springer Berlin Heidelberg :
|b Imprint: Springer,
|c 2012.
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|a XII, 176 p.
|b online resource.
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|a text
|b txt
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|a computer
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|a online resource
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|a text file
|b PDF
|2 rda
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|a Springer Theses, Recognizing Outstanding Ph.D. Research,
|x 2190-5053
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|a A Novel DNA Model -- Methods -- Finite Size Effects -- Structural and Mechanical Properties of Model DNA -- Thermodynamic Properties of Model DNA -- Modelling DNA Tweezers -- Modelling a DNA Walker.
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|a This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
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|a Physics.
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|a Polymers.
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|a Amorphous substances.
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|a Complex fluids.
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|a Biophysics.
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|a Biological physics.
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|a Statistical physics.
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|a Dynamical systems.
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|a Nanotechnology.
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|a Physics.
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|a Biophysics and Biological Physics.
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|a Nanotechnology.
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|a Polymer Sciences.
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|a Statistical Physics, Dynamical Systems and Complexity.
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|a Soft and Granular Matter, Complex Fluids and Microfluidics.
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|a SpringerLink (Online service)
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|t Springer eBooks
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|i Printed edition:
|z 9783642305160
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|a Springer Theses, Recognizing Outstanding Ph.D. Research,
|x 2190-5053
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|u http://dx.doi.org/10.1007/978-3-642-30517-7
|z Full Text via HEAL-Link
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|a ZDB-2-PHA
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|a Physics and Astronomy (Springer-11651)
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