Proteopathic Seeds and Neurodegenerative Diseases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Jucker, Mathias (Editor), Christen, Yves (Editor)
• Format: Electronic eBook
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
• Series: Research and Perspectives in Alzheimer's Disease,
• Subjects: Medicine.; Neurosciences.; Pharmacology.; Biomedicine.; Pharmacology/Toxicology.

The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans, and appears to occur many years before the onset of clinical symptoms. The initial cause of this pathogenic cascade and the means whereby disease spre...