Chemokine Biology — Basic Research and Clinical Application Volume I: Immunobiology of Chemokines /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Moser, Bernhard (Editor), Letts, Gordon L. (Editor), Neote, Kuldeep (Editor)
• Format: Electronic eBook
• Language: English
• Published: Basel : Birkhäuser Basel, 2006.
• Series: Progress in Inflammation Research
• Subjects: Medicine.; Immunology.; Pharmacology.; Cell biology.; Biomedicine.; Pharmacology/Toxicology.; Cell Biology.

The discovery of interleukin-8 close to 20 years ago initiated a new field of research touching on many aspects of immunology and inflammation. Interleukin-8 is just one member of a large class of structurally related chemoattractant proteins, known as chemokines. Chemokines are involved in the traf...

Table of Contents:

• Cellular targets in innate and adaptive immunity
• Traffic of T lymphocytes
• Lymphocyte homing to peripheral epithelial tissues
• Chemokine biology of NK cells and ?? T cells
• Dendritic cell traffic control by chemokines
• Chemokine receptor-mediated signal transduction
• Chemokines in leukocyte transendothelial migration
• Natural chemokine antagonism and synergism
• Effector cell traffic-unrelated functions
• Crosstalk between chemokine, opioid, and vanilloid receptors
• Antimicrobial and related activities of chemokines
• Virus-encoded chemokine modulators as novel anti-inflammatory reagents
• Chemokine receptors in tissue cells and angiogenesis.