Metallomics Recent Analytical Techniques and Applications /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ogra, Yasumitsu (Editor), Hirata, Takafumi (Editor)
• Format: Electronic eBook
• Language: English
• Published: Tokyo : Springer Japan : Imprint: Springer, 2017.
• Subjects: Medicine.; Human physiology.; Analytical chemistry.; Biochemistry.; Biomedicine.; Human Physiology.; Biochemistry, general.; Analytical Chemistry.

This book focuses on recent topics in metallomics, a study of the metallome, or metal-containing biomolecules. Metals can induce various physiological and toxicological effects in a very small amounts, in other words, the concentrations of biometals are very low in organisms. Thus, analytical techni...

Table of Contents:

• Part I Overview
• Chapter 1. Metallomics: Integrated Biometal Science
• Part II Analytical techniques and strategies surrounding metallomics
• Chapter 2. Speciation and identification of chalcogen-containing metabolites
• Chapter 3. Visualization of intracellular elements using scanning X-ray fluorescence microscopy
• Chapter 4. Quantitative elemental bioimaging protocol using femtosecond-Laser Ablation-ICP-Mass Spectrometry coupled with glass standard material
• Chapter 5. Single cells analysis by using ICP-MS
• Chapter 6. Synchrotron radiation X-ray analysis of metal accumulating plants
• Chapter 7. 77Se NMR Spectroscopy for Speciation Analysis of Selenium Compounds
• Chapter 8. Protein quantification and quantitative phosphorylation analysis by the determination of hetero atoms (S and P) by means of nanoHPLC-ICPMS
• Chapter 9. Analysis of drug active pharmaceutical ingredients and bio-molecules using triple quadrupole ICP-MS
• Chapter 10. Highly sensitive analysis of proteins and metabolites by metal tagging using LC-ICP-MS
• Part III Application of metallomics in molecular biology, medicine and pharmaceutical sciences
• Chapter 11. Comprehensive element analysis of prokaryotic and eukaryotic cells as well as organelles by ICP-MS
• Chapter 12. Iron isotope signature for red blood cell samples from Japanese female donors of various ages
• Chapter 13. Roles of zinc transporters in cellular transport of cadmium and manganese
• Chapter 14. Link between metal homeostasis and neurodegenerative diseases: crosstalk of metals and amyloidogenic proteins at the synapse
• Chapter 15. New insight into metallomics in cognition
• Chapter 16. Frontier of development for metallodrugs on the basis of metallomic pharmacology and medicinal inorganic chemistry.