DNA Alterations in Lynch Syndrome Advances in molecular diagnosis and genetic counselling /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vogelsang, Matjaž (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
• Subjects: Medicine.; Cancer research.; Human genetics.; Molecular biology.; Gastroenterology.; Oncology.; Biomedicine.; Cancer Research.; Human Genetics.; Molecular Medicine.

Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up,...