Notch Signaling Immunity and Cancer /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Yasutomo, Koji (Editor)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2017.
• Subjects: Medicine.; Cancer research.; Immunology.; Biomedicine.; Cancer Research.

This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differen...

Table of Contents:

• Preface
• Part I Immunology
• Ch1 Notch ligands for lymphocyte development
• Ch2 Notch controls the differentiation and function of cytotoxic CD8 T cells
• Ch3 Notch and myeloid cells
• Ch4 Taking CD4 T cells up a Notch
• Part II Cancer
• Ch5 NOTCH in malignant lymphoma
• Ch6 The two faces of Notch in solid cancers.