Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products

• Κύριος συγγραφέας: Noguchi, Taro (Συγγραφέας, http://id.loc.gov/vocabulary/relators/aut)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
• Έκδοση: 1st ed. 2018.
• Σειρά: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Θέματα: Medicinal chemistry.; Organic chemistry.; Pharmaceutical technology.; Medicinal Chemistry.; Organic Chemistry.; Pharmaceutical Sciences/Technology.

This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mi...

Πίνακας περιεχομένων:

• Introduction
• Development of a Mirror-image Screening Process by Using Synthetic Proteins
• Synthesis of Grb2 SH2 Domain Proteins for Mirror-image Screening Systems
• Conclusions.