Biopharmaceutical Applied Statistics Symposium Volume 3 Pharmaceutical Applications /

This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments - particularly biopharmaceutical clinical trials.  The papers were selected from invited presentations at the Biopharmaceutical Applied S...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Peace, Karl E. (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Chen, Ding-Geng (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt), Menon, Sandeep (Επιμελητής έκδοσης, http://id.loc.gov/vocabulary/relators/edt)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Singapore : Springer Singapore : Imprint: Springer, 2018.
Έκδοση:1st ed. 2018.
Σειρά:ICSA Book Series in Statistics,
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Part I: Personalized Medicine
  • 1 Targeted Learning of Optimal Individualized Treatment Rules under Cost Constraints
  • 2 Uses of Mixture Normal Distribution in Genomics and Otherwise
  • 3 Personalized Medicine - Design Considerations
  • 4 Adaptive Biomarker Subpopulation and Tumor Type Selection in Phase III Oncology Trials
  • 5 High Dimensional Data in Genomics
  • Part II:  Novel Applications
  • 6 Synergy or Additivity - The Importance of Defining the Primary Endpoint
  • 7 Full Bayesian Adaptive Dose Finding using Toxicity Probability Interval (TPI)
  • 8 Alpha-recycling for the Analyses of Primary and Secondary Endpoints of Clinical Trials
  • 9 Expanded Interpretations of Results of Carcinogenicity Studies of Pharmaceuticals
  • 1 Clinical Trials in Orphan Drug Development
  • 11 Mediation Modeling in Randomized Trials with Non-normal Outcome Variables
  • 12 Statistical Considerations in Using Images in Clinical Trials
  • 13 Interesting Applications over 30 Years of Consulting
  • 14 Uncovering Fraud, Misconduct and Other Data Quality Issues in Clinical Trials
  • 15 Development and Evaluation of High Dimensional Prognostic Models
  • 16 Design and Analysis of Biosimilar Studies.