Biopharmaceutical Applied Statistics Symposium Volume 3 Pharmaceutical Applications /
This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments - particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied S...
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| Other Authors: | , , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Singapore :
Springer Singapore : Imprint: Springer,
2018.
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| Edition: | 1st ed. 2018. |
| Series: | ICSA Book Series in Statistics,
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| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Part I: Personalized Medicine
- 1 Targeted Learning of Optimal Individualized Treatment Rules under Cost Constraints
- 2 Uses of Mixture Normal Distribution in Genomics and Otherwise
- 3 Personalized Medicine - Design Considerations
- 4 Adaptive Biomarker Subpopulation and Tumor Type Selection in Phase III Oncology Trials
- 5 High Dimensional Data in Genomics
- Part II: Novel Applications
- 6 Synergy or Additivity - The Importance of Defining the Primary Endpoint
- 7 Full Bayesian Adaptive Dose Finding using Toxicity Probability Interval (TPI)
- 8 Alpha-recycling for the Analyses of Primary and Secondary Endpoints of Clinical Trials
- 9 Expanded Interpretations of Results of Carcinogenicity Studies of Pharmaceuticals
- 1 Clinical Trials in Orphan Drug Development
- 11 Mediation Modeling in Randomized Trials with Non-normal Outcome Variables
- 12 Statistical Considerations in Using Images in Clinical Trials
- 13 Interesting Applications over 30 Years of Consulting
- 14 Uncovering Fraud, Misconduct and Other Data Quality Issues in Clinical Trials
- 15 Development and Evaluation of High Dimensional Prognostic Models
- 16 Design and Analysis of Biosimilar Studies.
