Co-signal Molecules in T Cell Activation Immune Regulation in Health and Disease /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Azuma, Miyuki (Editor, http://id.loc.gov/vocabulary/relators/edt), Yagita, Hideo (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Advances in Experimental Medicine and Biology, 1189
• Subjects: Immunology.; Cancer research.; Neurology .; Oncology .; Cancer Research.; Neurology.; Oncology.

This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of...

Table of Contents:

• Part I: Basic Understanding of Co-signal Molecules in T cell activation
• Chapter 1 Co-signal molecules in T cell activation
• Chapter 2 The CD28-B7 family of co-signaling molecules
• Chapter 3 The TNF YNFR family of co-signal molecules
• Chapter 4 Signal transduction via co-stimulatory and co-inhibitory receptors
• Chapter 5 Molecular dynamics of co-signal molecules in t cell activation
• Chapter 6 Role of co-stimulatory molecules in T helper cell differentiation
• Chapter 7 Control of regulatory T cells by co-signal molecules
• Part II: Co-signal Molecules in Health and Disease
• Chapter 8 Stimulatory and inhibitory co-signals in autoimmunity
• Chapter 9 Co-signaling molecules in neurological diseases
• Chapter 10 Costimulation blockade in transplantation
• Chapter 11 Immunotherapy targeting co-signal molecules. .