Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion

Malignant pleural effusion (MPE) is a frequent metastatic manifestation of human cancers. While we previously identified KRAS mutations as molecular culprits of MPE formation, the underlying mechanism remained unknown. Here, we determine that non-canonical IKKα-RelB pathway activation of KRAS-mutant...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Marazioti, Antonia, Lilis, Ioannis, Vreka, Malamati, Apostolopoulou, Hara, Kalogeropoulou, Argyro, Giopanou, Ioanna, Giotopoulou, Georgia, Krontira, Anthi, Iliopoulou, Marianthi, Kanellakis, Nikolaos, Agalioti, Theodora, Giannou, Anastasios, Jones-Paris, Celestial, Iwakura, Yoichiro, Kardamakis, Dimitrios, Blackwell, Timothy, Taraviras, Stavros, Spella, Magda, Stathopoulos, Georgios
Άλλοι συγγραφείς: Μαραζιώτη, Αντωνία
Μορφή: Journal (paper)
Γλώσσα:English
Έκδοση: 2018
Θέματα:
Διαθέσιμο Online:http://hdl.handle.net/10889/11464