Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion
Malignant pleural effusion (MPE) is a frequent metastatic manifestation of human cancers. While we previously identified KRAS mutations as molecular culprits of MPE formation, the underlying mechanism remained unknown. Here, we determine that non-canonical IKKα-RelB pathway activation of KRAS-mutant...
Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , |
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Άλλοι συγγραφείς: | |
Μορφή: | Journal (paper) |
Γλώσσα: | English |
Έκδοση: |
2018
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Θέματα: | |
Διαθέσιμο Online: | http://hdl.handle.net/10889/11464 |