Identification of RNA binding proteins as candidate therapeutic targets for the treatment of cancer

• Κύριος συγγραφέας: Καμζόλας, Ιωάννης
• Άλλοι συγγραφείς: Λυγερού, Ζωή
• Μορφή: Thesis
• Γλώσσα: English
• Έκδοση: 2019
• Θέματα: RNA binding proteins; Computational analysis; Drug screening; Data collection; RNA binding πρωτεΐνες; Υπολογιστική ανάλυση; Καρκινικοί ιστοί; 616.994 06

RNA binding proteins (RBPs) are proteins that bind to the RNA in cells and form ribonucleoprotein complexes. It is estimated that approximately 7.5% of all protein-coding genes in the human genome code for RBPs and their aberrant expression has profound effects on cellular physiology and the pathoge...