Validation of activity-based probes (ABPs) and inhibitors specific for the KLK6 protease in vitro

• Main Author: Γιαννακοπούλου, Χριστίνα
• Other Authors: Giannakopoulou, Christina
• Language: English
• Published: 2020
• Subjects: Kallikrein-related peptidase 6; Activity based probes; Theranostics; Ανθρώπινη καλλικρεΐνη 6

Kallikrein-related peptidase 6 (KLK6 for human; Klk6 for mouse) is a trypsin-like serine protease, member of the family of kallikrein-related (KLKs) serine proteases. Certain KLKs have been linked to various diseases, including autoimmune and inflammatory skin diseases, neurodegeneration, and multip...