Model based characterization of pharmacokinetic interaction between voriconazole and cytarabine in patients with acute myeloid leukemia
Voriconazole is a broad spectrum antifungal agent. Patients with acute myeloid leukemia that are susceptible to fungal infections receive simultaneously voriconazole and antitumor regimens. Drug-drug interactions between voriconazole and cytarabine involving the CYP3A4 enzyme are thought to affect t...
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Μορφή: | Thesis |
Γλώσσα: | English |
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2014
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Διαθέσιμο Online: | http://hdl.handle.net/10889/8097 |