The role of geminin in neural crest stem cells, a functional approach through bioinformatics analyses

• Main Author: Κανελλάκης, Νικόλαος Ι.
• Other Authors: Ταραβήρας, Σταύρος
• Format: Thesis
• Language: English
• Published: 2015
• Subjects: Neural crest; Geminin; Stem cells; Microarrays; Νευρική ακρολοφία; Βλαστοκύτταρα; 573.853 84

Geminin (Gmnn) is a nuclear protein that regulates the licensing of DNA replication, as well as cell fate decisions.1 To this end, it is becoming increasingly evident that Geminin regulates transcrip- tional programs associated with lineage specification. Neural crest cells (NCCs), which origina...