Protein modules and protein-protein interaction /

• Other Authors: Janin, Joël, Wodak, Shoshana J.
• Format: eBook
• Language: English
• Published: Amsterdam ; Boston : Academic Press, ©2002.
• Series: Advances in protein chemistry ; v. 61.
• Subjects: Proteins > Conformation.; Molecular recognition.; Proteins > genetics.; Protein Conformation.; Proteins > chemistry.; Proteins > physiology.; Electronic books.

Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modul...

Table of Contents:

• Structural basis of macromolecular recognition / Shoshana J. Wodak and Joël Janin
• Sequence analysis of multidomain proteins: past perspectives and future directions / Richard R. Copley [and others]
• Identification of transiently interacting proteins and of stable protein complexes / Bertrand Séraphin
• Molecular recognition in antibody-antigen complexes / Eric J. Sundberg and Roy A. Mariuzza
• Molecular recognition by SH2 domains / J. Michael Bradshaw and Gabriel Waksman
• How SH3 domains recognize proline / Andrea Musacchio
• Structural biology of elF4F: mRNA recognition and preparation in eukaryotic translation initiation / Joseph Marcotrigiano and Stephen K. Burley.