Membrane proteins as drug targets /

• Other Authors: Lunn, Charles A. (Charles Albert)
• Format: eBook
• Language: English
• Published: Amsterdam ; Boston : Elsevier/Academic Press, ©2010.
• Series: Progress in molecular biology and translational science ; v. 91.
• Subjects: Drug development.; Membrane proteins.; MEDICAL > Drug Guides.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; MEDICAL > Nursing > Pharmacology.; Electronic books.

Membrane proteins continue to be prime drug targets because they perform essential processes in the cell including controlling the flow of information and materials between cells and mediating activities like hormone action and nerve impulses. The study of membrane proteins could lead to€new and imp...

Table of Contents:

• Inverse agonism at serotonin and cannabinoid receptors / Vincent J. Aloyo [and others]
• G protein-coupled receptor heteromers as new targets for drug development / Sergi Ferré [and others]
• Receptor activity modifying proteins and their potential as drug targets / Denise L. Wootten [and others]
• Regulators of G protein signaling proteins as targets for drug discovery / Benita Sjögren, Levi L. Blazer, and Richard R. Neubig
• Escorts take the lead: molecular chaperones as therapeutic targets / Dumaine Williams and Lakshmi A. Devi
• The T1R2/T1R3 sweet receptor and TRPMS ion channel: taste targets with therapeutic potential / Dennis Sprous and Kyle R. Palmer
• Challenges and approaches for assay development of membrane and membrane-associated proteins in drug discovery / Scott Gridley, Anthony L. Shrout, and Edward A. Esposito.