Prodrugs and Targeted Delivery : Towards Better ADME Properties.

• Corporate Author: Wiley InterScience (Online service)
• Other Authors: Rautio, Jarkko, Mannhold, Raimund, 1948-, Kubinyi, Hugo
• Format: eBook
• Language: English
• Published: Weinheim : Wiley-VCH, [2011]
• Series: Methods and principles in medicinal chemistry.
• Subjects: Prodrugs.; Pharmacy.; Medicine.; Drug Delivery Systems.; MEDICAL > Drug Guides.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; MEDICAL > Nursing > Pharmacology.; Electronic books.

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning...