Prodrugs and Targeted Delivery : Towards Better ADME Properties.

This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: Wiley InterScience (Online service)
Άλλοι συγγραφείς: Rautio, Jarkko, Mannhold, Raimund, 1948-, Kubinyi, Hugo
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Weinheim : Wiley-VCH, [2011]
Σειρά:Methods and principles in medicinal chemistry.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Περιγραφή
Περίληψη:This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
Φυσική περιγραφή:1 online resource (522 pages).
Βιβλιογραφία:Includes bibliographical references (pages 473-481) and index.
ISBN:9783527633166
3527633162
9783527633173
3527633170
1283140578
9781283140577
9783527326037
3527326030
DOI:10.1002/9783527633166