Prodrugs and Targeted Delivery : Towards Better ADME Properties.
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning...
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| Other Authors: | , , |
| Format: | eBook |
| Language: | English |
| Published: |
Weinheim :
Wiley-VCH,
[2011]
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| Series: | Methods and principles in medicinal chemistry.
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| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
| Summary: | This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs. Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development. |
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| Physical Description: | 1 online resource (522 pages). |
| Bibliography: | Includes bibliographical references (pages 473-481) and index. |
| ISBN: | 9783527633166 3527633162 9783527633173 3527633170 1283140578 9781283140577 9783527326037 3527326030 |
| DOI: | 10.1002/9783527633166 |
