Clinical trial design : Bayesian and frequentist adaptive methods /

• Main Author: Yin, Guosheng (Author)
• Corporate Author: Wiley InterScience (Online service)
• Format: eBook
• Language: English
• Published: Hoboken, N.J. : John Wiley & Sons, [2012]
• Series: Wiley series in probability and statistics.
• Subjects: Clinical trials > Statistical methods.; Bayesian statistical decision theory.; Mathematical statistics.; Clinical Trials as Topic > methods.; Bayes Theorem.; Statistics as Topic > methods.; Clinical trials.; Medicine.; MEDICAL > Laboratory Medicine.; Electronic books.

There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This bo...