Clinical trial design : Bayesian and frequentist adaptive methods /

• Κύριος συγγραφέας: Yin, Guosheng (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: Wiley InterScience (Online service)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : John Wiley & Sons, [2012]
• Σειρά: Wiley series in probability and statistics.
• Θέματα: Clinical trials > Statistical methods.; Bayesian statistical decision theory.; Mathematical statistics.; Clinical Trials as Topic > methods.; Bayes Theorem.; Statistics as Topic > methods.; Clinical trials.; Medicine.; MEDICAL > Laboratory Medicine.; Electronic books.
• Φυσική περιγραφή: 1 online resource (xvii, 336 pages) : illustrations.
• Βιβλιογραφία: Includes bibliographical references and indexes.
• ISBN: 9781118183335; 1118183339; 9781118183304; 1118183304
• DOI: 10.1002/9781118183335

There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. nevertheless, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. This book provides an overview of the fundamentals of clinical trials, the key terminologies and concepts, and a brief review and comparison on Bayesian and frequentist estimation and inference procedures. From the practical point of view, this book introduces various statistical methods that are commonly.