Down Syndrome : from Understanding the Neurobiology to Therapy /

• Other Authors: Dierssen, Mara (Editor), Torre, Rafael de la (Editor)
• Format: eBook
• Language: English
• Published: Amsterdam : Elsevier, 2012.
• Series: Progress in brain research ; v. 197.
• Subjects: Down syndrome.; Developmental neurobiology.; Down Syndrome > genetics.; Down Syndrome > therapy.; Neurobiology.; Electronic books.

Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of th...