Bioisosteres in medicinal chemistry.

• Συγγραφή απο Οργανισμό/Αρχή: Wiley InterScience (Online service)
• Άλλοι συγγραφείς: Brown, Nathan (Medicinal chemist), Mannhold, Raimund, 1948-, Kubinyi, Hugo, Folkers, Gerd
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken : Sons, John Wiley & amp ; 2012.
• Σειρά: Methods and principles in medicinal chemistry ; v. 54.
• Θέματα: Drugs > Design.; Pharmaceutical chemistry.; MEDICAL > Drug Guides.; MEDICAL > Nursing > Pharmacology.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; Electronic books.

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first par...