Functional neural transplantation IV : translation to clinical application. Part A /

• Other Authors: Dunnett, S. B. (Stephen B.) (Editor), Björklund, Anders (Editor)
• Format: eBook
• Language: English
• Published: Cambridge, MA : Academic Press is an imprint of Elsevier, 2017.
• Edition: First edition.
• Series: Progress in brain research ; v. 230.
• Subjects: Stem cells > Transplantation.; Brain > Regeneration.; HEALTH & FITNESS / Diseases / General; MEDICAL / Clinical Medicine; MEDICAL / Diseases; MEDICAL / Evidence-Based Medicine; MEDICAL / Internal Medicine; Stem Cell Transplantation > methods.; Nervous System Diseases > therapy.; Neurodegenerative Diseases > therapy.; Brain Injuries > therapy.; Nerve Regeneration.; Electronic books.

"Functional Neural Transplantation IV: Translation to Clinical Application, Volume 230 provides a survey of the current status of cell transplantation in the nervous system, with a focus on the conditions for achieving structural repair and functional recovery after brain damage or in neurodege...

Table of Contents:

• Mechanisms and use of neural transplants for brain repair / Stephen B. Dunnett and Anders Björklund
• Reprogramming of somatic cells: iPS and iN cells / Vania Broccoli
• Brain repair from intrinsic cell sources: turning reactive glia into neurons / Olof Torper and Magdalena Götz
• Ex vivo gene therapy for the treatment of neurological disorders / Genevieve Gowing , Soshana Svendsen and Clive N. Svendsen
• Preparation, characterization and banking of clinical-grade cells for neural transplantation: scale up, fingerprinting and genomic stability of stem cell lines / Ammar Natalwala and Tilo Kunath
• Regulatory considerations for pluripotent stem cell therapies / Melissa K. Carpenter
• Strategies for bringing stem cell-derived dopamine neurons to the clinic: a European approach (STEM-PD) / Agnete Kirkeby, Malin Parmar and Roger A. Barker
• Strategies for bringing stem cell-derived dopamine neurons to the clinic: the NYSTEM trial / Lorenz Studer
• Strategies for bringing stem cell-derived dopamine neurons to the clinic: the Kyoto trial / Jun Takahashi
• From open to large-scale randomised cell transplantation trials in Huntington's disease: lessons from the multicentric intracerebral grafting in Huntington's Disease trial (MIG-HD) and previous pilot studies / Anne-Catherine Bachoud-Lévi
• Pluripotent stem cell-derived neurons for transplantation in Huntington's disease / Meng Li and Anne E. Rosser
• Advanced imaging of transplant survival, fate, differentiation, and integration / Nadja Van Camp, Elsa Diguet and Philippe Hantraye
• Rehabilitation training in neural restitution / Susanne Clinch, Monica Busse, Mate D. Döbrössy and Stephen B. Dunnett.