Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models

• Κύριοι συγγραφείς: Tveito, Aslak (Συγγραφέας), Lines, Glenn T. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Σειρά: Lecture Notes in Computational Science and Engineering, 111
• Θέματα: Mathematics.; Computer graphics.; Computer mathematics.; Computational Science and Engineering.; Biomedicine general.; Computer Imaging, Vision, Pattern Recognition and Graphics.

Flow of ions through voltage gated channels can be represented theoretically using stochastic differential equations where the gating mechanism is represented by a Markov model. The flow through a channel can be manipulated using various drugs, and the effect of a given drug can be reflected by chan...