Xenopus development /
"Xenopus frogs have long been used as model organisms in basic and biomedical research. These frogs have helped unlock basic developmental and cellular processes that have led to scientific breakthroughs and have had practical application in cancer research and regenerative medicine. Xenopus De...
| Μορφή: | Ηλ. βιβλίο |
|---|---|
| Γλώσσα: | English |
| Έκδοση: |
Hoboken, NJ : Malden, MA :
Wiley-Blackwell,
2014.
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Xenopus Development; Copyright; Contents; Contributors; Preface; Section I Oocyte and Early Embryo; 1 Transcription in the Xenopus Oocyte Nucleus; Introduction; LBC structure: The standard model; Chromomeres and loops; Transcription on LBC loops; Transcripts produced during oogenesis; In situ hybridization of nascent transcripts on individual LBC loops; Appendix; Acknowledgments; References; 2 RNA Localization during Oogenesis in Xenopus laevis; Xenopus oocytes as a model system for exploring RNA localization; Cis -elements and the role of short repeated motifs.
- Proteins, RNAs, and the endoplasmic reticulumMechanism(s) for RNA localization to the vegetal cortex; Looking toward the future; References; 3 From Oocyte to Fertilizable Egg: Regulated mRNA Translation and the Control of Maternal Gene Expression; Mechanisms of mRNA translational control: Global versus selective targeting; Sequestration of maternal mRNA contributes to control of gene expression during Xenopus oogenesis; Future perspectives; Acknowledgments; References; 4 Polarity of Xenopus Oocytes and Early Embryos; Oocyte polarity and embryonic axes.
- Development of A-V polarity during oogenesisVegetal hemisphere maternal factors; Vegetal cortex; Animal hemisphere maternal factors; Asymmetry of inorganic maternal factors; Maternal determination of planar and basolateral polarity and L-R asymmetry; Conclusions; References; 5 Germ-Cell Specification in Xenopus; Background; Formation of the Xenopus germline; Molecular components of germ plasm; Do chromatin modifications play a role in Xenopus PGC specification?; Concluding remarks; Acknowledgments; References; Section II Midblastula Transition, Gastrulation, and Neurulation.
- 6 The Xenopus Embryo as a Model System to Study Asymmetric Furrowing in Vertebrate Epithelial CellsIntroduction; MELK is a cell cycle-regulated kinase involved in development and cancer; MELK in Xenopus laevis embryo cytokinesis; Asymmetric furrowing is a mode of cytokinesis conserved throughout evolution; The Xenopus embryo as a model system to analyze asymmetric furrowing; Conclusions; Acknowledgments; References; 7 Induction and Differentiation of the Xenopus Ciliated Embryonic Epidermis; Introduction; Nonneural ectoderm specification; Ontogeny of the mucociliary epithelium.
- Perspectives and outstanding questionsConcluding remarks; References; 8 Wnt Signaling during Early Xenopus Development; Introduction; Wnt "canonical" and "noncanonical" pathways: Complexity and uncertainties; Major processes regulated by Wnts during early Xenopus development; Wnt signaling at postgastrula stages; References; 9 Neural Tube Closure in Xenopus; Introduction; Narrowing and elongation of the neural plate; Cell-shape changes causing neural tube morphogenesis; Complete tube closure assisted by nonneural ectoderm; References; Section III Metamorphosis and Organogenesis.
